Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors while in the central anxious process, conolidine modulates alternate molecular targets. A Science Improvements analyze located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://felixazrlc.isblog.net/an-unbiased-view-of-alternative-natural-pain-relief-to-replace-traditional-painkillers-56031265