Pentobarbital will decrease the level or effect of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of levoketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. When barbiturates like Nembutal are abused, they are not usually the primary drug of... https://bookmarklayer.com/story20334073/5-fatti-facile-circa-pentobarbital-natrium-descritto