This review proposes that K2's large adverse effect incidence is thanks, at the very least partially, to distinct JWH-018 metabolite exercise with the cannabinoid one receptor (CB1R), and indicates that metabolites of most drugs, but not the carboxy metabolite, retain in vitro As well as in vivo activity at CB1Rs. https://jamesd172ula6.blogunteer.com/30364038/details-fiction-and-mam-2201