When specified concomitantly with promethazine, the dose of barbiturates ought to be decreased by at least one-half, and also the dose of narcotics need to be reduced by 1-quarter to one-half. Dosage have to be individualized. Excessive quantities of promethazine HCl relative to your narcotic may well bring on restlessness https://wockusa.com/product/oxycodone-20mg/